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| 白芍、黄芪及蒲公英中33种禁用农药残留分析及风险评估 |
| Determination and Risk Assessment of 33 Banned Pesticides Residues in Paeoniae Radix Alba, Astragali Radix and Taraxaci Herba |
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| DOI： |
| 中文关键词: 白芍 黄芪 蒲公英 禁用农药残留 风险评估 |
| 英文关键词:Paeoniae Radix Alba Astragali Radix Taraxaci Herba Banned pesticides residues Risk assessment |
| 基金项目:国家中医药管理局科技专项项目（GZY-KJS-2023-036）；陕西省卫生健康委员会-秦药质量控制与创新产品研发创新团队；陕西重点研发计划-重点项目（S2024-YF-ZDXM-SF-0355）；陕西省中医药管理局项目（SZY-KJCYC-2025-JC-045）；西安市科技计划医学研究一般项目（24YXYJ0167）。 |
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| 中文摘要: |
| 采用气相色谱-质谱法对白芍、黄芪、蒲公英药材饮片进行禁用农药残留检测，对3种药材饮片中禁用农药残留的急性、慢性摄入风险，以点评估方式进行计算，再根据英国兽药残留风险排序矩阵计算各农药的风险得分。结果表明:3种药材饮片中共检出10种禁用农药，其中检出率最高的是六六六、滴滴涕和涕灭威，检出率均为58.33%，超标率最高的是六六六、滴滴涕和甲拌磷，均为25.00%；10种禁用农药的ADI%、ARfD%均小于2.0%，膳食暴露风险处于较低水平；涕灭威在3种药材饮片中的残留风险最高，特丁硫磷在白芍、黄芪中残留风险较高；其中黄芪的各项禁用农药残留风险均略高于白芍、蒲公英。检测结果表明3种药材中禁用农药残留检出量均较低，无重大健康风险。 |
| 英文摘要: |
| Paeoniae Radix Alba, Astragali Radix and Taraxaci Herba were tested for banned pesticide residues using gas chromatography-mass spectrometry (GC-MS).The acute and chronic dietary intake risks of the pesticide residues were calculated using the point assessment method, and risk scores were derived based on the UK Veterinary Residues Committee (VRC) matrix ranking.Ten banned pesticides were detected in the three types of herbal slices. The highest detection rates—58.33%—were observed for hexachlorocyclohexane, dichlorodiphenyltrichloroethane (DDT), and aldicarb. The highest exceedance rates—25.00%—were reported for hexachlorocyclohexane, DDT, and phorate. The chronic and acute intake risks of these 10 banned pesticides were all less than 2.0%, indicating that the dietary exposure risk is low. Among the detected compounds, aldicarb posed the highest residual risk across all three herbs, while terbufos exhibited a relatively higher residual risk in Paeoniae Radix Alba and Astragali Radix. Overall, Astragali Radix showed slightly higher levels of pesticide risk compared to the other two herbs. Although certain banned pesticides were detected, the overall contamination levels were low and posed no significant health risk under current exposure levels. |
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